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Pioneering topological methods for network-based drug–target prediction by exploiting a brain-network self-organization theory
The bipartite network representation of the drug–target interactions (DTIs) in a biosystem enhances understanding of the drugs’ multifaceted action modes, suggests therapeutic switching for approved drugs and unveils possible side effects. As experimental testing of DTIs is costly and time-consuming...
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| Publié dans: | Brief Bioinform |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291778/ https://ncbi.nlm.nih.gov/pubmed/28453640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx041 |
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