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Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity
BACKGROUND. Morbidity and mortality associated with Clostridioides (formerly Clostridium) difficile infection (CDI) rises progressively with advanced age (≥ 65 years) due in part to perturbations of the gut microbiota and immune dysfunction. Epidemiological data of community-acquired CDI suggests in...
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| Publicat a: | Anaerobe |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291369/ https://ncbi.nlm.nih.gov/pubmed/30099125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.anaerobe.2018.07.011 |
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