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Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays
Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestinal crypt cell regeneration. Motivated by the observ...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291236/ https://ncbi.nlm.nih.gov/pubmed/30540745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207140 |
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