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Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays

Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestinal crypt cell regeneration. Motivated by the observ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zeng, Xin, Kirkpatrick, Robert, Hofmann, Glenn, Grillot, Didier, Linhart, Valerie, Viviani, Fabrice, Marino, Joseph, Boyer, Joseph, Graham, Taylor L., Lu, Quinn, Wu, Zining, Benowitz, Andrew, Cousins, Rick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291236/
https://ncbi.nlm.nih.gov/pubmed/30540745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207140
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