Blocking Autophagy in Cancer-Associated Fibroblasts Supports Chemotherapy of Pancreatic Cancer Cells

In this study we evaluated the interaction of pancreatic cancer cells, cancer-associated fibroblasts, and distinct drugs such as α-cyano-4-hydroxycinnamate, metformin, and gemcitabine. We observed that α-cyano-4-hydroxycinnamate as monotherapy or in combination with metformin could significantly ind...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhang, Xianbin, Schönrogge, Maria, Eichberg, Johanna, Wendt, Edgar Heinz Uwe, Kumstel, Simone, Stenzel, Jan, Lindner, Tobias, Jaster, Robert, Krause, Bernd Joachim, Vollmar, Brigitte, Zechner, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290725/
https://ncbi.nlm.nih.gov/pubmed/30568920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00590
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