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The STING-STAT6 Pathway Drives Cas9-induced Host Response in Human Monocytes
Cas9 (CRISPR associated protein 9) is an RNA-guided DNA endonuclease enzyme derived from Streptococcus that has been widely used for genome editing in a variety of organisms, including humans. Here, we report that exogenous Cas9 protein can elicit an inflammatory immune response through the release...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290677/ https://ncbi.nlm.nih.gov/pubmed/30348526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.10.080 |
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