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Structural attributes of mammalian prion infectivity: Insights from studies with synthetic prions
Prion diseases are neurodegenerative disorders that affect many mammalian species. Mammalian prion proteins (PrPs) can misfold into many different aggregates. However, only a small subpopulation of these structures is infectious. One of the major unresolved questions in prion research is identifying...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290147/ https://ncbi.nlm.nih.gov/pubmed/30275016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005622 |
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