Biomarkers for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Associated With Hexanucleotide Expansion Mutations in C9orf72

Now that genetic testing can identify persons at risk for developing amyotrophic lateral sclerosis (ALS) many decades before symptoms begin, there is a critical need for biomarkers that signal the onset and progression of degeneration. The search for candidate disease biomarkers in patients with mut...

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Bibliographic Details
Published in:Front Neurol
Main Authors: Floeter, Mary Kay, Gendron, Tania F.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neurology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289985/
https://ncbi.nlm.nih.gov/pubmed/30568632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.01063
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