C9orf72 Hexanucleotide Repeat Expansion and Guam Amyotrophic Lateral Sclerosis–Parkinsonism-Dementia Complex

IMPORTANCE: High-prevalence foci of amyotrophic lateral sclerosis (ALS) and parkinsonism-dementia complex (PDC) exist in Japanese on the Kii Peninsula of Japan and in the Chamorros of Guam. Clinical and neuropathologic similarities suggest that the disease in these 2 populations may be related. Rece...

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Main Authors: Dombroski, Beth A., Galasko, Douglas R., Mata, Ignacio F., Zabetian, Cyrus P., Craig, Ulla-Katrina, Garruto, Ralph M., Oyanagi, Kiyomitsu, Schellenberg, Gerard D.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771869/
https://ncbi.nlm.nih.gov/pubmed/23588498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.1817
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