BAFF inhibits autophagy promoting cell proliferation and survival by activating Ca(2+)-CaMKII-dependent Akt/mTOR signaling pathway in normal and neoplastic B-lymphoi d cells

B cell activating factor from the TNF family (BAFF) is implicated in not only the physiology of normal B cells, but also the pathophysiology of aggressive B cells related to malignant and autoimmune diseases. Autophagy plays a crucial role in balancing the beneficial and detrimental effects of immun...

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Pubblicato in:Cell Signal
Autori principali: Dong, Xiaoqing, Qin, Jiamin, Ma, Jing, Zeng, Qingyu, Zhang, Hai, Zhang, Ruijie, Liu, Chunxiao, Xu, Chong, Zhang, Shuangquan, Huang, Shile, Chen, Long
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289808/
https://ncbi.nlm.nih.gov/pubmed/30244168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.09.012
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