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Data-driven modeling of mitochondrial dysfunction in Alzheimer’s disease

Intracellular accumulation of oligomeric forms of β amyloid (Aβ) are now believed to play a key role in the earliest phase of Alzheimer(′)s disease (AD) as their rise correlates well with the early symptoms of the disease. Extensive evidence points to impaired neuronal Ca(2+) homeostasis as a direct...

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Bibliografiske detaljer
Udgivet i:Cell Calcium
Main Authors: Toglia, Patrick, Demuro, Angelo, Daniel Mak, Don-On, Ullah, Ghanim
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289702/
https://ncbi.nlm.nih.gov/pubmed/30248575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2018.09.003
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