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Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments
Methods to systematically study subcellular RNA localization are limited and lagging behind proteomic tools. Here, we combined APEX2-mediated proximity biotinylation of proteins with photoactivatable ribonucleoside-enhanced crosslinking to simultaneously profile the proteome, as well as the transcri...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289640/ https://ncbi.nlm.nih.gov/pubmed/30478324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0220-y |
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