MMP-9 inhibitors impair learning in spontaneously hypertensive rats

Vascular cognitive impairment dementia (VCID) is a major cause of cognitive loss in the elderly. Matrix metalloproteinases (MMPs) are a family of proteases involved in remodeling the extracellular matrix in development, injury and repair. Blood-brain barrier (BBB) disruption due to inflammation medi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Raz, Limor, Yang, Yi, Thompson, Jeffrey, Hobson, Sasha, Pesko, John, Mobashery, Shahriar, Chang, Mayland, Rosenberg, Gary
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289411/
https://ncbi.nlm.nih.gov/pubmed/30533010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208357
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