Pharmacological and functional comparisons of α6/α3β2β3-nAChRs and α4β2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line

Neuronal nicotinic acetylcholine receptors containing α6 subunits (α6(*)-nAChRs) show highly restricted distribution in midbrain neurons associated with pleasure, reward, and mood control, suggesting an important impact of α6(*)-nAChRs in modulating mesolimbic functions. However, the function and ph...

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Détails bibliographiques
Publié dans:Acta Pharmacol Sin
Auteurs principaux: Chen, De-jie, Gao, Fen-fei, Ma, Xiao-kuang, Shi, Gang-gang, Huang, Yuan-bing, Su, Quang-xi, Sudweeks, Sterling, Gao, Ming, Dharshaun, Turner, Eaton, Jason Brek, Chang, Yong-chang, Mcintosh, J Michael, Lukas, Ronald J, Whiteaker, Paul, Steffensen, Scott C, Wu, Jie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289390/
https://ncbi.nlm.nih.gov/pubmed/29795357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.209
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