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Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis

Major depressive disorder is a common but devastating mental disorder, and recent evidence shows that neuroinflammation may play a pivotal role in the etiology of depression. Astragaloside IV (AS-IV) is an active component purifed from Astragalus membranaceus (Fisch) Bge, which has shown anti-inflam...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Song, Mei-ting, Ruan, Jie, Zhang, Ru-yi, Deng, Jie, Ma, Zhan-qiang, Ma, Shi-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289360/
https://ncbi.nlm.nih.gov/pubmed/29795356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.208
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