Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors

Mice subjected to prenatal restraint stress (PRS mice) showed biochemical and behavioral abnormalities consistent with a schizophrenia-like phenotype (Matrisciano et al., 2016). PRS mice are characterized by increased DNA-methyltransferase 1 (DNMT1) and ten-eleven methylcytosine dioxygenase 1 (TET1)...

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Udgivet i:Front Mol Neurosci
Main Authors: Matrisciano, Francesco, Dong, Erbo, Nicoletti, Ferdinando, Guidotti, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289213/
https://ncbi.nlm.nih.gov/pubmed/30564095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00423
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