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Activation of Group II Metabotropic Glutamate Receptors Promotes DNA Demethylation in the Mouse Brain
Activation of group II metabotropic glutamate receptors (mGlu2 and -3 receptors) has shown a potential antipsychotic activity, yet the underlying mechanism is only partially known. Altered epigenetic mechanisms contribute to the pathogenesis of schizophrenia and currently used medications exert chro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127529/ https://ncbi.nlm.nih.gov/pubmed/21505039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070896 |
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