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Activation of Group II Metabotropic Glutamate Receptors Promotes DNA Demethylation in the Mouse Brain

Activation of group II metabotropic glutamate receptors (mGlu2 and -3 receptors) has shown a potential antipsychotic activity, yet the underlying mechanism is only partially known. Altered epigenetic mechanisms contribute to the pathogenesis of schizophrenia and currently used medications exert chro...

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מידע ביבליוגרפי
Main Authors: Matrisciano, Francesco, Dong, Erbo, Gavin, David Peter, Nicoletti, Ferdinando, Guidotti, Alessandro
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127529/
https://ncbi.nlm.nih.gov/pubmed/21505039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070896
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