Differential Roles of IL-2 Signaling in Developing versus Mature Tregs

Although Foxp3(+) regulatory T cells (Tregs) require interleukin-2 (IL-2) for their development, it has been unclear whether continuing IL-2 signals are needed to maintain lineage stability, survival, and suppressor function in mature Tregs. We generated mice in which CD25, the main ligand-binding s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Fan, Martin Y., Low, Jun Siong, Tanimine, Naoki, Finn, Kelsey K., Priyadharshini, Bhavana, Germana, Sharon K., Kaech, Susan M., Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289175/
https://ncbi.nlm.nih.gov/pubmed/30380412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados