Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs

Other than more widely used methods, the use of styrene maleic acid allows the direct extraction of membrane proteins from the lipid bilayer into SMALPs keeping it in its native lipid surrounding. Here we present the combined use of SMALPs and LILBID-MS, allowing determination of oligomeric states o...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Hellwig, Nils, Peetz, Oliver, Ahdash, Zainab, Tascón, Igor, Booth, Paula J., Mikusevic, Vedrana, Diskowski, Marina, Politis, Argyris, Hellmich, Yvonne, Hänelt, Inga, Reading, Eamonn, Morgner, Nina
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2018
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289172/
https://ncbi.nlm.nih.gov/pubmed/30452022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc06284f
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