The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer

BACKGROUND: The peritoneum is one of the most frequent metastatic sites in pancreatic cancer patients, and peritoneal dissemination makes this disease refractory due to aggressive progression and chemoresistance. Although the role of the tumor microenvironment in cancer development is recognized, th...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Kuwada, Kazuya, Kagawa, Shunsuke, Yoshida, Ryuichi, Sakamoto, Shuichi, Ito, Atene, Watanabe, Megumi, Ieda, Takeshi, Kuroda, Shinji, Kikuchi, Satoru, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288926/
https://ncbi.nlm.nih.gov/pubmed/30537992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0981-2
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