The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer

BACKGROUND: The peritoneum is one of the most frequent metastatic sites in pancreatic cancer patients, and peritoneal dissemination makes this disease refractory due to aggressive progression and chemoresistance. Although the role of the tumor microenvironment in cancer development is recognized, th...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Kuwada, Kazuya, Kagawa, Shunsuke, Yoshida, Ryuichi, Sakamoto, Shuichi, Ito, Atene, Watanabe, Megumi, Ieda, Takeshi, Kuroda, Shinji, Kikuchi, Satoru, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288926/
https://ncbi.nlm.nih.gov/pubmed/30537992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0981-2
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