The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer

BACKGROUND: The peritoneum is one of the most frequent metastatic sites in pancreatic cancer patients, and peritoneal dissemination makes this disease refractory due to aggressive progression and chemoresistance. Although the role of the tumor microenvironment in cancer development is recognized, th...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Kuwada, Kazuya, Kagawa, Shunsuke, Yoshida, Ryuichi, Sakamoto, Shuichi, Ito, Atene, Watanabe, Megumi, Ieda, Takeshi, Kuroda, Shinji, Kikuchi, Satoru, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288926/
https://ncbi.nlm.nih.gov/pubmed/30537992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0981-2
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