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Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis

BACKGROUND: Lung macrophages are major participants in the pulmonary innate immune response. In the cystic fibrosis (CF) lung, the inability of lung macrophages to successfully regulate the exaggerated inflammatory response suggests dysfunctional innate immune cell function. In this study, we aim to...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Chen, Youdinghuan, Armstrong, David A., Salas, Lucas A., Hazlett, Haley F., Nymon, Amanda B., Dessaint, John A., Aridgides, Daniel S., Mellinger, Diane L., Liu, Xiaoying, Christensen, Brock C., Ashare, Alix
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288922/
https://ncbi.nlm.nih.gov/pubmed/30526669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0580-2
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