Liquid biopsy using the supernatant of a pleural effusion for EGFR genotyping in pulmonary adenocarcinoma patients: a comparison between cell-free DNA and extracellular vesicle-derived DNA

BACKGROUND: EGFR genotyping in pulmonary adenocarcinoma patients who develop pleural effusions is mostly performed using cytology or cell block slides with low sensitivity. Liquid biopsy using the supernatant of pleural effusions may be more effective because they contain many components released by...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Lee, Jong Sik, Hur, Jae Young, Kim, In Ae, Kim, Hee Joung, Choi, Chang Min, Lee, Jae Chol, Kim, Wan Seop, Lee, Kye Young
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288853/
https://ncbi.nlm.nih.gov/pubmed/30526536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5138-3
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