Liquid biopsy using the supernatant of a pleural effusion for EGFR genotyping in pulmonary adenocarcinoma patients: a comparison between cell-free DNA and extracellular vesicle-derived DNA

BACKGROUND: EGFR genotyping in pulmonary adenocarcinoma patients who develop pleural effusions is mostly performed using cytology or cell block slides with low sensitivity. Liquid biopsy using the supernatant of pleural effusions may be more effective because they contain many components released by...

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Udgivet i:BMC Cancer
Main Authors: Lee, Jong Sik, Hur, Jae Young, Kim, In Ae, Kim, Hee Joung, Choi, Chang Min, Lee, Jae Chol, Kim, Wan Seop, Lee, Kye Young
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288853/
https://ncbi.nlm.nih.gov/pubmed/30526536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5138-3
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