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The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs

Lytic infection of human parvovirus B19 (B19V) takes place exclusively in human erythroid progenitor cells of bone marrow and fetal liver, which disrupts erythropoiesis. During infection, B19V expresses three nonstructural proteins (NS1, 11-kDa, and 7.5-kDa) and two structural proteins (VP1 and VP2)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Xu, Peng, Chen, Aaron Yun, Ganaie, Safder S., Cheng, Fang, Shen, Weiran, Wang, Xiaomei, Kleiboeker, Steve, Li, Yi, Qiu, Jianming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288338/
https://ncbi.nlm.nih.gov/pubmed/30282717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01464-18
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