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Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice

Many preclinically promising therapies for diabetic kidney disease fail to provide efficacy in humans, reflecting limited quantitative translational understanding between rodent models and human disease. To quantitatively bridge interspecies differences, we adapted a mathematical model of renal func...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Mahato, Hari Shankar, Ahlstrom, Christine, Jansson-Löfmark, Rasmus, Johansson, Ulrika, Helmlinger, Gabriel, Hallow, K. Melissa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288095/
https://ncbi.nlm.nih.gov/pubmed/30564457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0077-9
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