Autophagy maintains tumor growth through circulating arginine

Autophagy captures intracellular components and delivers them to lysosomes where they are degraded and recycled to sustain metabolism and to enable survival in starvation(1–5). Acute, whole-body deletion of the essential autophagy gene Atg7 in adult mice causes a systemic metabolic defect manifested...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Poillet-Perez, Laura, Xie, Xiaoqi, Zhan, Le, Yang, Yang, Sharp, Daniel W., Hu, Zhixian Sherrie, Su, Xiaoyang, Maganti, Anurag, Jiang, Cherry, Lu, Wenyun, Zheng, Haiyan, Bosenberg, Marcus W., Mehnert, Janice M., Guo, Jessie Yanxiang, Lattime, Edmund, Rabinowitz, Joshua D., White, Eileen
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287937/
https://ncbi.nlm.nih.gov/pubmed/30429607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0697-7
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