Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma

Nearly half of melanoma patients develop brain metastases during the course of their disease. Despite advances in both localized radiation and systemic immunotherapy, brain metastases remain difficult to treat, with most patients surviving less than 5 months from the time of diagnosis. While both tr...

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Publicat a:Oncoimmunology
Autors principals: Pfannenstiel, Lukas W., McNeilly, Corey, Xiang, Chaomei, Kang, Kai, Diaz-Montero, Claudia Marcella, Yu, Jennifer S., Gastman, Brian R.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287893/
https://ncbi.nlm.nih.gov/pubmed/30546944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1507669
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