Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma

Nearly half of melanoma patients develop brain metastases during the course of their disease. Despite advances in both localized radiation and systemic immunotherapy, brain metastases remain difficult to treat, with most patients surviving less than 5 months from the time of diagnosis. While both tr...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Pfannenstiel, Lukas W., McNeilly, Corey, Xiang, Chaomei, Kang, Kai, Diaz-Montero, Claudia Marcella, Yu, Jennifer S., Gastman, Brian R.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287893/
https://ncbi.nlm.nih.gov/pubmed/30546944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1507669
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