Effect of combined anti-PD-1 and temozolomide therapy in glioblastoma

Background: Although programmed death-1 (PD-1) blockade is effective in treating several types of cancer, the efficacy of this agent in glioblastoma (GBM) is largely unknown. Methods: We evaluated therapeutic effects of anti-PD-1, temozolomide (TMZ), and their combination in an orthotopic murine GBM...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Park, Junseong, Kim, Chang Gon, Shim, Jin-Kyoung, Kim, Jong Hoon, Lee, Hoyoung, Lee, Jae Eun, Kim, Min Hwan, Haam, Keeok, Jung, Inkyung, Park, Su-Hyung, Chang, Jong Hee, Shin, Eui-Cheol, Kang, Seok-Gu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287793/
https://ncbi.nlm.nih.gov/pubmed/30546966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1525243
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