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Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres

Resident cancer cells with stem cell-like features induce drug tolerance, facilitating survival of glioblastoma (GBM). We previously showed that strategies targeting tumor bioenergetics present a novel emerging avenue for treatment of GBM. The objective of this study was to enhance the therapeutic e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Park, Hun Ho, Park, Junseong, Cho, Hye Joung, Shim, Jin-Kyoung, Moon, Ju Hyung, Kim, Eui Hyun, Chang, Jong Hee, Kim, Soo Youl, Kang, Seok-Gu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827959/
https://ncbi.nlm.nih.gov/pubmed/33429981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020282
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