Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

Multiple immunotherapeutics have been approved for cancer patients, however advanced solid tumors are frequently refractory to treatment. We evaluated the safety and immunogenicity of a vaccination approach with multimodal oncolytic potential in non-human primates (NHP) (Macaca fascicularis). Primat...

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書誌詳細
出版年:Oncoimmunology
主要な著者: Pol, Jonathan G., Acuna, Sergio A., Yadollahi, Beta, Tang, Nan, Stephenson, Kyle B., Atherton, Matthew J., Hanwell, David, El-Warrak, Alexander, Goldstein, Alyssa, Moloo, Badru, Turner, Patricia V., Lopez, Roberto, LaFrance, Sandra, Evelegh, Carole, Denisova, Galina, Parsons, Robin, Millar, Jamie, Stoll, Gautier, Martin, Chantal G., Pomoransky, Julia, Breitbach, Caroline J., Bramson, Jonathan L., Bell, John C., Wan, Yonghong, Stojdl, David F., Lichty, Brian D., McCart, J. Andrea
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287790/
https://ncbi.nlm.nih.gov/pubmed/30546947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1512329
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