Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

Multiple immunotherapeutics have been approved for cancer patients, however advanced solid tumors are frequently refractory to treatment. We evaluated the safety and immunogenicity of a vaccination approach with multimodal oncolytic potential in non-human primates (NHP) (Macaca fascicularis). Primat...

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Publicado en:Oncoimmunology
Main Authors: Pol, Jonathan G., Acuna, Sergio A., Yadollahi, Beta, Tang, Nan, Stephenson, Kyle B., Atherton, Matthew J., Hanwell, David, El-Warrak, Alexander, Goldstein, Alyssa, Moloo, Badru, Turner, Patricia V., Lopez, Roberto, LaFrance, Sandra, Evelegh, Carole, Denisova, Galina, Parsons, Robin, Millar, Jamie, Stoll, Gautier, Martin, Chantal G., Pomoransky, Julia, Breitbach, Caroline J., Bramson, Jonathan L., Bell, John C., Wan, Yonghong, Stojdl, David F., Lichty, Brian D., McCart, J. Andrea
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287790/
https://ncbi.nlm.nih.gov/pubmed/30546947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1512329
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