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Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy. External supplementation of spermidine extends lifespan and health span across species, including in yeast, nematodes, flies and mice. In humans, spermidine levels decline with aging, and a possible connection...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Madeo, Frank, Bauer, Maria A., Carmona-Gutierrez, Didac, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287690/
https://ncbi.nlm.nih.gov/pubmed/30306826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1530929
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