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ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis

ZFYVE26/Spastizin and SPG11/Spatacsin encode 2 large proteins that are mutated in hereditary autosomal-recessive spastic paraplegia/paraparesis (HSP) type 15 (AR-SPG15) and type 11 (AR-SPG11), respectively. We previously have reported that AR-SPG15-related ZFYVE26 mutations lead to autophagy defects...

詳細記述

保存先:
書誌詳細
出版年:Autophagy
主要な著者: Vantaggiato, Chiara, Panzeri, Elena, Castelli, Marianna, Citterio, Andrea, Arnoldi, Alessia, Santorelli, Filippo Maria, Liguori, Rocco, Scarlato, Marina, Musumeci, Olimpia, Toscano, Antonio, Clementi, Emilio, Bassi, Maria Teresa
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287682/
https://ncbi.nlm.nih.gov/pubmed/30081747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1507438
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