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Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation
Autophagy allows cells to adapt to changes in their environment by coordinating the degradation and recycling of cellular components and organelles to maintain homeostasis. Lysosomes are organelles critical for terminating autophagy via their fusion with mature autophagosomes to generate autolysosom...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348974/ https://ncbi.nlm.nih.gov/pubmed/25365221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77598 |
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