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Triplet CFTR modulators: future prospects for treatment of cystic fibrosis
Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Researchers ha...
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| Publicado no: | Ther Clin Risk Manag |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287538/ https://ncbi.nlm.nih.gov/pubmed/30584312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S147164 |
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