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Triplet CFTR modulators: future prospects for treatment of cystic fibrosis

Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Researchers ha...

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Bibliografische gegevens
Gepubliceerd in:Ther Clin Risk Manag
Hoofdauteur: Chaudary, Nauman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287538/
https://ncbi.nlm.nih.gov/pubmed/30584312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S147164
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