Quercetin inhibits transforming growth factor β1-induced epithelial–mesenchymal transition in human retinal pigment epithelial cells via the Smad pathway

PURPOSE: The purpose of this study was to evaluate the effect and mechanism of quercetin on TGF-β1-induced retinal pigment epithelial (RPE) cell proliferation, migration, and extracellular matrix secretion. MATERIALS AND METHODS: Cell counting kit-8, transwell, wound-healing assays, and ELISA were u...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Cai, Wenting, Yu, Donghui, Fan, Jiaqi, Liang, Xiuwei, Jin, Huizi, Liu, Chang, Zhu, Meijiang, Shen, Tianyi, Zhang, Ruiling, Hu, Weinan, Wei, Qingquan, Yu, Jing
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287523/
https://ncbi.nlm.nih.gov/pubmed/30584279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S185618
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