17β-estradiol ameliorates oxidative stress and blue light-emitting diode-induced retinal degeneration by decreasing apoptosis and enhancing autophagy

PURPOSE: This study aimed to assess the effects of 17β-estradiol (βE(2)) on blue light-emitting diode (LED)-induced retinal degeneration (RD) in rats and hydrogen peroxide (H(2)O(2))-induced retinal pigment epithelium cell injury in humans and elucidate the protective mechanism of βE(2) underlying t...

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Foilsithe in:Drug Des Devel Ther
Main Authors: Wei, Qingquan, Liang, Xiuwei, Peng, Ye, Yu, Donghui, Zhang, Ruiling, Jin, Huizi, Fan, Jiaqi, Cai, Wenting, Ren, Chengda, Yu, Jing
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2018
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129027/
https://ncbi.nlm.nih.gov/pubmed/30233136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S176349
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