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Imbalance of Amniotic Fluid Activin-A and Follistatin in Intraamniotic Infection, Inflammation, and Preterm Birth

CONTEXT: Microbial invasion of the amniotic fluid (AF) cavity stimulates an inflammatory response that involves activin-A, a pleiotropic mediator member of the TGFβ superfamily involved in connective tissue remodeling. The role of AF follistatin, a natural inhibitor of activin-A, in inflammation-ind...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Hardy, John T., Buhimschi, Irina A., McCarthy, Megan E., Zhao, Guomao, Laky, Christine A., Shook, Lydia L., Buhimschi, Catalin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287504/
https://ncbi.nlm.nih.gov/pubmed/27159193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-4147
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