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Polymer Size Affects Biodistribution and Placental Accumulation of the Drug Delivery Biopolymer Elastin-Like Polypeptide in a Rodent Pregnancy Model
INTRODUCTION. Fusion of therapeutic agents to Elastin-like Polypeptide (ELP) is a novel drug delivery strategy for prevention of placental drug transfer. Previous studies have used a 60 kDa ELP tag for this purpose. However, placental transfer of ELP may be size dependent. The goal of this study was...
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| Publicado no: | Placenta |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287274/ https://ncbi.nlm.nih.gov/pubmed/30501877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2018.10.005 |
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