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B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding

CD22 and Siglec-G are members of the Siglec family. Both are inhibitory co-receptors on the surface of B cells and inhibit B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. CD22 functions predominantly as an inhibitor on conventional...

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發表在:Front Immunol
Main Authors: Meyer, Sarah J., Linder, Alexandra T., Brandl, Carolin, Nitschke, Lars
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286995/
https://ncbi.nlm.nih.gov/pubmed/30559744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02820
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