Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruses in bats, and the ability of Tylonycteris-BatCoV HKU4 spike protein to utilize MERS-CoV receptor, human dipeptidyl peptidase 4 hDPP4, suggest a bat ancestral origin of MERS-CoV. We developed 12 primary bat ce...

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Udgivet i:Emerg Microbes Infect
Main Authors: Lau, Susanna K. P., Fan, Rachel Y. Y., Luk, Hayes K. H., Zhu, Longchao, Fung, Joshua, Li, Kenneth S. M., Wong, Emily Y. M., Ahmed, Syed Shakeel, Chan, Jasper F. W., Kok, Raven K. H., Chan, Kwok-Hung, Wernery, Ulrich, Yuen, Kwok-Yung, Woo, Patrick C. Y.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286955/
https://ncbi.nlm.nih.gov/pubmed/30531999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0208-9
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