Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruses in bats, and the ability of Tylonycteris-BatCoV HKU4 spike protein to utilize MERS-CoV receptor, human dipeptidyl peptidase 4 hDPP4, suggest a bat ancestral origin of MERS-CoV. We developed 12 primary bat ce...

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Détails bibliographiques
Publié dans:Emerg Microbes Infect
Auteurs principaux: Lau, Susanna K. P., Fan, Rachel Y. Y., Luk, Hayes K. H., Zhu, Longchao, Fung, Joshua, Li, Kenneth S. M., Wong, Emily Y. M., Ahmed, Syed Shakeel, Chan, Jasper F. W., Kok, Raven K. H., Chan, Kwok-Hung, Wernery, Ulrich, Yuen, Kwok-Yung, Woo, Patrick C. Y.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286955/
https://ncbi.nlm.nih.gov/pubmed/30531999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0208-9
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