Comparison of molecular testing modalities for detection of ROS1 rearrangements in a cohort of positive patient samples

INTRODUCTION –: ROS1 gene fusions are a well-characterized class of oncogenic driver found in approximately 1-2% of non-small cell lung cancer patients. ROS1-directed therapy in these patients is more efficacious and is associated with fewer side effects compared to chemotherapy and is thus now cons...

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Библиографические подробности
Опубликовано в: :J Thorac Oncol
Главные авторы: Davies, Kurtis D., Le, Anh T., Sheren, Jamie, Nijmeh, Hala, Gowan, Katherine, Jones, Kenneth L., Varella-Garcia, Marileila, Aisner, Dara L., Doebele, Robert C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286810/
https://ncbi.nlm.nih.gov/pubmed/29935306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.05.041
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