Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes

Ultraviolet B (UVB) irradiation activates the aryl hydrocarbon receptor (AHR), generates the reactive oxygen species (ROS), and induces the production of proinflammatory cytokines such as IL1A, IL1B, and IL6. 6-Formylindolo[3,2-b]carbazole (FICZ) is a tryptophan-derived photoproduct that is induced...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Tanaka, Yuka, Uchi, Hiroshi, Hashimoto-Hachiya, Akiko, Furue, Masutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286782/
https://ncbi.nlm.nih.gov/pubmed/30595799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9298052
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