Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosis

BACKGROUND: Hepatocyte is particularly vulnerable to apoptosis, a hallmark of many liver diseases. Although pro-apoptotic mechanisms have been extensively explored, less is known about the hepatocyte-specific anti-apoptotic molecular events and it lacks effective approach to combat hepatocyte apopto...

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Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Wang, Hong, Ge, Chaoliang, Zhou, Jiyu, Guo, Yitong, Cui, Shuang, Huang, Ningning, Yan, Tingting, Cao, Lijuan, Che, Yuan, Zheng, Qiuling, Zheng, Xiao, Gonzalez, Frank J., Wang, Guangji, Hao, Haiping
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286639/
https://ncbi.nlm.nih.gov/pubmed/30337250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.028
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