Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer

BACKGROUND: NSCLC (non-small-cell lung cancer) is the leading cause of cancer-related mortality worldwide. Both epigenetic and genetic changes contribute to the initiation, development and metastasis of NSCLC. Recently, accumulating data have begun to support the notion that long noncoding RNAs (lnc...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Shi, Xuefei, Liu, Zhili, Liu, Zhicong, Feng, Xueren, Hua, Feng, Hu, Xixian, Wang, Bin, Lu, Kaihua, Nie, Fengqi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286630/
https://ncbi.nlm.nih.gov/pubmed/30314898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.004
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