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A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease

BACKGROUND: The quantification of amyloid-beta (Aβ) peptides in blood plasma as potential biomarkers of Alzheimer’s disease (AD) is hampered by very low Aβ concentrations and the presence of matrix components that may interfere with the measurements. METHODS: We developed a two-step immunoassay for...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Shahpasand-Kroner, Hedieh, Klafki, Hans-W., Bauer, Chris, Schuchhardt, Johannes, Hüttenrauch, Melanie, Stazi, Martina, Bouter, Caroline, Wirths, Oliver, Vogelgsang, Jonathan, Wiltfang, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286509/
https://ncbi.nlm.nih.gov/pubmed/30526652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0448-x
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