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A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease
BACKGROUND: The quantification of amyloid-beta (Aβ) peptides in blood plasma as potential biomarkers of Alzheimer’s disease (AD) is hampered by very low Aβ concentrations and the presence of matrix components that may interfere with the measurements. METHODS: We developed a two-step immunoassay for...
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| Publicado no: | Alzheimers Res Ther |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6286509/ https://ncbi.nlm.nih.gov/pubmed/30526652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0448-x |
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