From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo

The neural crest (NC) is a transient embryonic stem cell-like population characterized by its multipotency and broad developmental potential. Here, we perform NC-specific transcriptional and epigenomic profiling of foxd3-mutant cells in vivo to define the gene regulatory circuits controlling NC spec...

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Publicat a:Dev Cell
Autors principals: Lukoseviciute, Martyna, Gavriouchkina, Daria, Williams, Ruth M., Hochgreb-Hagele, Tatiana, Senanayake, Upeka, Chong-Morrison, Vanessa, Thongjuea, Supat, Repapi, Emmanouela, Mead, Adam, Sauka-Spengler, Tatjana
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286384/
https://ncbi.nlm.nih.gov/pubmed/30513303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.11.009
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